Recombinant human tPA protein (His tag)

 Description

Product name

Recombinant human tPA protein (His tag)

Known as

Tissue-type plasminogen activator; t-plasminogen activator; t-PA

Expression system

HEK 293 cells

Tags

His tag C-terminus

Specifications

SDS-PAGE

61 kDa, reducing conditions

Purity

>95% SDS-PAGE

Form

Lyophilized powder

Stability and Storage

Storage

Store at -20 ~ -80℃, avoid repeated freeze/ thaw cycle

Stability

Store at –20℃for 12 months, or reconstitute for 3 months.

Constituents

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4.

General information

Function

Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.

Images

Human tPA (His Tag) on SDS-PAGE under reducing condition(R). The gel was visualized by Coomassie®Blue Staining. The purity of the protein is greater than 95%.