Recombinant human PAI-1 protein (His tag)

 Description

Product name

Recombinant human PAI-1 protein (His tag)

Known as

Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; Serpin E1

Expression system

HEK 293 cells

Tags

His tag C-terminus

Specifications

SDS-PAGE

44.2 kDa, reducing conditions

Purity

>95% SDS-PAGE

Form

Lyophilized powder

Stability and Storage

Storage

Store at -20 ~ -80℃, avoid repeated freeze/ thaw cycle

Stability

Store at –20℃for 12 months, or reconstitute for 3 months.

Constituents

Lyophilized from 0.22 μm filtered solution in PBS, Ph7.4.

General information

Function

Serine protease inhibitor. Inhibits TMPRSS7; Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots; Acts as a regulator of cell migration, independently of its role as protease inhibitor.

Images

Human PAI-1 (His Tag) on SDS-PAGE under reducing condition(R). The gel was visualized by Coomassie®Blue Staining. The purity of the protein is greater than 95%.