Recombinant human Thrombomodulin protein (His tag)

 Description

Product name

Recombinant human Thrombomodulin protein (His tag)

Known as

TM; Fetomodulin; CD141; AHUS 6

Expression system

HEK 293 cells

Tags

His tag C-terminus

Specifications

SDS-PAGE

40 kDa, reducing conditions

Purity

>95% SDS-PAGE

Form

Lyophilized powder

Stability and Storage

Storage

Store at -20 ~ -80℃, avoid repeated freeze/ thaw cycle

Stability

Aliquot and store at –20℃ for 12 months.

Constituents

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 and 5% trehalose.

General information

Function

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Images

Human Thrombomodulin (His Tag) on SDS-PAGE under reducing condition(R). The gel was visualized by Coomassie?Blue Staining. The purity of the protein is greater than 95%.