Recombinant human Her-2 protein (His tag with a TEV cleavage site)

 Description

Product name

Recombinant human Her-2 protein (His tag)

Known as

Receptor tyrosine-protein kinase erbB-2; MLN 19; CD340; yrosine kinase-type cell surface receptor HER2

Expression system

HEK 293 cells

Tags

His tag C-terminus

Specifications

SDS-PAGE

100 kDa, reducing conditions

Purity

>95% SDS-PAGE

Form

Lyophilized powder

Stability and Storage

Storage

Store at -20 ~ -80℃, avoid repeated freeze/ thaw cycle

Stability

Aliquot and store at –20℃ for 12 months.

Constituents

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 and 5% trehalose.

General information

Function

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs).

Images

Human Her-2 (His Tag) on SDS-PAGE under reducing condition(R). The gel was visualized by Coomassie®Blue Staining. The purity of the protein is greater than 95%.