Recombinant human IL-10 protein (His tag）

Description

Product name Recombinant human IL-10 protein (His tag)

Known as Interleukin-10

Expression system HEK 293 cells

Tags His tag C-terminus

Specifications

SDS-PAGE 17 kDa, reducing conditions

Purity >95% SDS-PAGE

Form Lyophilized powder

Stability and Storage

Storage Store at -20 ~ -80℃, avoid repeated freeze/ thaw cycle

Stability Aliquot and store at –20℃ for 12 months.

Constituents Lyophilized from 0.22 μm filtered solution in PBS, pH 8.0.

General information

Function Major immune regulatory cytokine that acts on many cells of the immune system

where it has profound anti-inflammatory functions, limiting excessive tissue

disruption caused by inflammation. Mechanistically, IL10 binds to its

heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and

STAT2-mediated phosphorylation of STAT3.

Images

Human IL-10 (His Tag) on SDS-PAGE under reducing

condition(R). The gel was visualized by Coomassie®

Blue Staining. The purity of the protein is greater than

95%.