Leupeptin
Braveds
Description
Product Name | Leupeptin |
Types | S homologous reagent |
Form | powder |
CAS NO | 103476-89-7 |
Producer | China |
Purity | microbial, ≥90% (HPLC) |
Storage | -20°C |
Synonyms |
Overview
Biological source | microbial |
Dissolubility | H2O: soluble50 mg/mL |
Dissolubility | H2O: soluble10 mM (Solutions are stable for a week at 4 C. Stock solutions are stable up to 6 months at -20°C.) |
Biochemical / physiological behavior.
Serine and cysteine protease inhibitors. Inhibit plasmin, trypsin, papain, calpain and cathepsin B. It did not inhibit pepsin, cathepsin An and D, thrombin or α-chymotrypsin. The effective concentration is 10-100 μ M. Many studies have used leucostatin to prevent hearing loss caused by auditory overstimulation or ototoxic antibiotics such as gentamicin. The loss of cochlear hair cells is thought to be mediated by calpain.).
Analysis consideration.
Due to the equilibrium of the three forms in solution, leucoinhibitory peptides can form multiple peaks on HPLC. The purity was determined by three main peaks. The main impurity peptide is racemic leucopeptide.
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SKU | UNIT | PRICE (USD) | QTY |
---|---|---|---|
SG12870-5MG | 5MG | 97.4 | |
SG12870-25MG | 25MG | 309.8 | |
SG12870-100MG | 100MG | 1185 |