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2-Iminothiolane hydrochloride

Braveds
Description
Product Name 2-Iminothiolane hydrochloride
Types S homologous reagent
Form powder
CAS NO 4781-83-3
Producer China
Purity >=98% (TLC), powder
Storage 2-8°C
Synonyms
Overview
Impurity <=5% Free sulfhydryl groups
Dissolubility H2O: soluble100 mg/mL
Melting point 198-201°C(lit.)
Storage 2-8°C
Form powder
Content >=98% (TLC)

Application.
2-iminosulfide heterocyclopentane hydrochloride has been used in the synthesis of mercaptoglycol (polyethylene glycol). It can be used to synthesize PLA-SH (polyethylene glycol-mercaptan) and PLA-PEG-SH (polyethylene glycol-polylactic acid-mercaptan).

Mercaptan reagent of primary amine. The free sulfhydryl group was obtained by the reaction of amidine bond under pH 7-10. It can be used to prepare disulfide and / or thioether bonded conjugates.

Other considerations.
Note that the amidine bond retains the positive charge of the primary amine. A connecting arm containing five atoms.

General description.
2-iminosulfide heterocyclopentane hydrochloride (2-IT.HCl) is a protein modification reagent, which is usually used to connect mercaptan groups to proteins and peptides. The Raman spectra of hair keratin fibers modified with 2-IT.HCl showed the formation of new disulfide groups.

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SKU UNIT PRICE (USD) QTY
SG17728-100MG 100MG 51.6
SG17728-1G 1G 381.3