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(Z)-4-Hydroxytamoxifen

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Description
Product Name (Z)-4-Hydroxytamoxifen
Types S homologous reagent
Form powder
CAS NO 68047-06-3
Producer China
Purity ≥94% (Z Isomer)
Storage 2-8°C,避光
Recertification 3Years
Synonyms Tamoxifen - SG15569-1G
Tamoxifen Solution - SG37891-10ML
Tamoxifen - SG56488-1G
Tamoxifen Solution - SG56842-10ML
Overview

Storage conditions are dry and avoid light.
Storage temperature 2-8 °C.
Soluble methanol: 10 mg/mL; ethanol: 20 mg/mL (heating).

Biochemical / physiological behavior.
4-hydroxytamoxifen (4-OHT) is an active metabolite of tamoxifen, which combines estrogen receptor (ER) and estrogen-related receptor (ERR) to produce estrogenic and antiestrogenic effects. It is a selective estrogen receptor modulator (SERM) that can be permeated by cells. In the genetic engineering of Cas9 variants of ligand-dependent introns, 4-hydroxytamoxifen is used to control the Cas9 function that weakens the targeting effect in CRISPR-mediated gene editing.

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SKU UNIT PRICE (USD) QTY
SG79043-5MG 5MG 141.6
SG79043-25MG 25MG 596.3