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5-Fluorouracil

Braveds
Description
Product Name 5-Fluorouracil
Types S homologous reagent
Form powder
CAS NO 51-21-8
Producer China
Purity >=99% (HPLC), powder
Storage RT
Recertification 4Years
Synonyms
Overview
Dissolubility methanol: soluble
Dissolubility 1 M NH4OH: soluble
Dissolubility DMSO/DMF: soluble
Color white
Gene information human ... TYMS(7298)
Melting point  282-286°C (dec.)(lit.)
Content  >=99% (HPLC)
Form powder

Biochemical / physiological behavior.
An effective antineoplastic drug that consumes intracellular dTTP pools by affecting pyrimidine synthesis by inhibiting thymidylate synthase. It is metabolized into ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. 5-FU treatment of cells leads to the accumulation of S-phase cells and has been shown to induce p53-dependent apoptosis.

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SKU UNIT PRICE (USD) QTY
SG18182-1G 1G 34.8
SG18182-5G 5G 86.1