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Etoposide

Braveds
Description
Product Name Etoposide
Types S homologous reagent
Form powder
CAS NO 33419-42-0
Producer China
Application DNA synthesis | interferes
Purity synthetic, >=98%, powder
Storage RT
Recertification 4Years
Synonyms
Overview
Form powder
Melting point 236-251°C(lit.)
Gene information human ... ABCB1(5243), CYP3A4(1576), TOP2A(7153)mouse ... Abcb1a(18671), Abcb1b(18669)rat ... Top2a(360243)
PKa value 9.8
Dissolubility DMSO: soluble30 mg/mL
Color white
Content >=98%
Mechanism  DNA synthesis | interferes
Mechanism  enzyme | inhibits
Biological source synthetic

Biochemical / physiological behavior.
Etoposide is an anti-tumor agent, which can be combined with topoisomerase II and DNA to enhance double-strand and single-strand cleavage of DNA and reversibly inhibit rearrangement. Block the cell cycle in S phase and G2 phase of the cell cycle; induce apoptosis in normal and tumor cells; inhibit the synthesis of oncoprotein Mdm2 and induce apoptosis in tumor cell lines that overexpress Mdm2.

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SKU UNIT PRICE (USD) QTY
SG01505-25MG 25MG 22.7
SG01505-100MG 100MG 57.9